The Common Mechanism
Safeguard
your synthesis
Commec is a free, open-source, globally-available tool for DNA synthesis screening.
The Common Mechanism
Commec is a free, open-source, globally-available tool for DNA synthesis screening.
Commec screens every order for biosecurity risks and regulatory compliance, while your data stays entirely under your control.
Stay ahead of biosecurity best practices and growing regulatory requirements, with AI-resilient screening that tracks evolving standards and national policies.
Tailor results to your and your customers' location with coverage of US and UK guidance and export controls from China, India, the Australia Group, and more.
Commec is free to install, fully open-source, and light enough to run on a laptop. Development and integration is supported by IBBIS, a Swiss non-profit foundation.
Commec tells you if an order needs attention — flagging sequences of concern, finding matches to regulated pathogens, and clearing the rest.
Benchmarked & validated
Sensitive detection of sequences of concern, evaluated against NIST benchmarks, with <2% false positives on synbio constructs.
Resilient to AI designs
Tested against AI-generated and obfuscated variants, as reported in Science, maintaining detection for novel sequences.
Local-first & private
Runs entirely on your own infrastructure, with open-source code and <10 GB of downloads. Your sequence data never leaves your systems.
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